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NCLEX-RN (Registered Nurse) Practice Exam · Question

A patient with a penicillin allergy is prescribed cefazolin. What action should the nurse take?

Cefazolin (a cephalosporin) has a potential cross-sensitivity with penicillin. The nurse should hold the medication and notify the prescriber to clarify the ord

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Question: A patient with a penicillin allergy is prescribed cefazolin. What action should the nurse take?

Answer options:

  • Administer the medication as ordered. ✅ Hold the medication and notify the prescriber.
  • Administer a test dose first.
  • Monitor for a severe allergic reaction.

Correct answer: Hold the medication and notify the prescriber.

Explanation: Cefazolin (a cephalosporin) has a potential cross-sensitivity with penicillin. The nurse should hold the medication and notify the prescriber to clarify the order and ensure patient safety.

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