A nurse is administering a unit of packed red blood cells (PRBCs) to a client. Fifteen minutes after the infusion begins, the client reports feeling 'itchy all over' and has generalized urticaria. Which action should the nurse take FIRST?

Question: A nurse is administering a unit of packed red blood cells (PRBCs) to a client. Fifteen minutes after the infusion begins, the client reports feeling 'itchy all over' and has generalized urticaria. Which action should the nurse take FIRST?

Answer options:

• Slow down the infusion rate and monitor the client closely.
• Administer diphenhydramine as per protocol. ✅ Stop the transfusion immediately.
• Elevate the client's legs and administer oxygen.

Correct answer: Stop the transfusion immediately.

Explanation: The client is exhibiting signs of an acute allergic transfusion reaction (urticaria, itching). The immediate priority is to stop the transfusion to prevent further exposure to the allergen and worsening of the reaction. Subsequent actions would include maintaining IV access, notifying the HCP, and administering medications as ordered.