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NCLEX-RN (Registered Nurse) Practice Exam · Question

The nurse is reviewing the medication administration record for a new admission with myasthenia gravis. The client is prescribed pyridostigmine. Understanding the pathophysiology of myasthenia gravis, what is the primary expected outcome of this medication?

Myasthenia gravis is characterized by a reduction in acetylcholine receptors at the neuromuscular junction. Pyridostigmine is an acetylcholinesterase inhibitor,

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Question: The nurse is reviewing the medication administration record for a new admission with myasthenia gravis. The client is prescribed pyridostigmine. Understanding the pathophysiology of myasthenia gravis, what is the primary expected outcome of this medication?

Answer options:

  • Decrease muscle inflammation. ✅ Enhance acetylcholine receptor activity.
  • Inhibit autoimmune antibody production.
  • Reduce muscular spasticity.

Correct answer: Enhance acetylcholine receptor activity.

Explanation: Myasthenia gravis is characterized by a reduction in acetylcholine receptors at the neuromuscular junction. Pyridostigmine is an acetylcholinesterase inhibitor, which increases the amount of available acetylcholine to bind with the remaining receptors, thus improving muscle strength.

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