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First Aid & CPR Practice · Question

What is the first-line emergency treatment for severe anaphylaxis?

Epinephrine auto-injector IM into the outer mid-thigh is first-line for anaphylaxis. Call 9-1-1.

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Question: What is the first-line emergency treatment for severe anaphylaxis?

Answer options:

  • Antihistamine tablet ✅ Intramuscular epinephrine (e.g., EpiPen) into the outer thigh
  • Cold water on the face
  • Oral salbutamol

Correct answer: Intramuscular epinephrine (e.g., EpiPen) into the outer thigh

Explanation: Epinephrine auto-injector IM into the outer mid-thigh is first-line for anaphylaxis. Call 9-1-1.

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