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Canadian Pharmacist Qualifying Exam Practice · Question

A drug has a half-life of 6 hours. If a patient takes a single dose of 100 mg, approximately how much of the drug will remain in the body after 18 hours?

After 1 half-life (6 hours), 50% (50 mg) remains. After 2 half-lives (12 hours), 25% (25 mg) remains. After 3 half-lives (18 hours), 12.5% (12.5 mg) remains.

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Question: A drug has a half-life of 6 hours. If a patient takes a single dose of 100 mg, approximately how much of the drug will remain in the body after 18 hours?

Answer options:

  • 50 mg
  • 25 mg ✅ 12.5 mg
  • 6.25 mg

Correct answer: 12.5 mg

Explanation: After 1 half-life (6 hours), 50% (50 mg) remains. After 2 half-lives (12 hours), 25% (25 mg) remains. After 3 half-lives (18 hours), 12.5% (12.5 mg) remains.

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