Canadian Pharmacist Qualifying Exam Practice · Question
A 60-year-old male with a history of heart failure (NYHA Class III) is prescribed furosemide 40 mg daily. Furosemide acts by inhibiting the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle. This mechanism classifies furosemide as which type of drug?
Drugs that inhibit the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle are classified as loop diuretics. Furosemide is a potent loop diu
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Question: A 60-year-old male with a history of heart failure (NYHA Class III) is prescribed furosemide 40 mg daily. Furosemide acts by inhibiting the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle. This mechanism classifies furosemide as which type of drug?
Answer options:
- Thiazide diuretic
- Potassium-sparing diuretic ✅ Loop diuretic
- Carbonic anhydrase inhibitor
Correct answer: Loop diuretic
Explanation: Drugs that inhibit the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle are classified as loop diuretics. Furosemide is a potent loop diuretic, commonly used in conditions like heart failure.
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