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Canadian Pharmacist Qualifying Exam Practice · Question

A 60-year-old male is prescribed a new fluticasone/salmeterol (Advair Diskus) 250/50 mcg twice daily for COPD. During counseling, he asks if he should rinse his mouth after using the inhaler. What is the primary reason for this recommendation?

Rinsing the mouth and gargling with water after using an inhaled corticosteroid is crucial to minimize the local deposition of the steroid in the mouth and thro

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Question: A 60-year-old male is prescribed a new fluticasone/salmeterol (Advair Diskus) 250/50 mcg twice daily for COPD. During counseling, he asks if he should rinse his mouth after using the inhaler. What is the primary reason for this recommendation?

Answer options:

  • To prevent dental caries from the inhaled powder.
  • To reduce the systemic absorption of the active ingredients. ✅ To minimize the risk of developing oral candidiasis (thrush).
  • To improve the taste of the medication in his mouth.

Correct answer: To minimize the risk of developing oral candidiasis (thrush).

Explanation: Rinsing the mouth and gargling with water after using an inhaled corticosteroid is crucial to minimize the local deposition of the steroid in the mouth and throat, thereby reducing the risk of developing oral candidiasis (thrush). This does not significantly reduce systemic absorption or impact dental caries or taste as the primary reason.

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