Canadian Pharmacist Qualifying Exam Practice · Question
You need to prepare 500 mL of an 8% salicylic acid in paraffin ointment. You have 3% and 15% salicylic acid paraffin ointments available. How much of the 3% ointment is required?
Using alligation: (Desired concentration - Lower concentration) / (Higher concentration - Lower concentration) = Ratio of lower concentration product. (8% - 3%)
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Question: You need to prepare 500 mL of an 8% salicylic acid in paraffin ointment. You have 3% and 15% salicylic acid paraffin ointments available. How much of the 3% ointment is required?
Answer options:
- 167 mL
- 208 mL
- 292 mL ✅ 333 mL
Correct answer: 333 mL
Explanation: Using alligation: (Desired concentration - Lower concentration) / (Higher concentration - Lower concentration) = Ratio of lower concentration product. (8% - 3%) / (15% - 3%) = 5 / 12. This means for every 12 parts total, 5 parts come from the 15% ointment, and 7 parts come from the 3% ointment. Since we need 500 mL total, the amount of 3% ointment needed is (7/12) * 500 mL = 291.67 mL.
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