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Canadian Pharmacist Qualifying Exam Practice · Question

A 45-year-old female weighing 60 kg is to receive a loading dose of aminophylline 6 mg/kg over 30 minutes. Aminophylline is available as an injectable solution of 25 mg/mL. How many milliliters of aminophylline should be added to the infusion bag?

The total loading dose required is 6 mg/kg * 60 kg = 360 mg. Since the available concentration is 25 mg/mL, the volume needed is 360 mg / 25 mg/mL = 14.4 mL.

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Question: A 45-year-old female weighing 60 kg is to receive a loading dose of aminophylline 6 mg/kg over 30 minutes. Aminophylline is available as an injectable solution of 25 mg/mL. How many milliliters of aminophylline should be added to the infusion bag?

Answer options:

  • 14.4 mL ✅ 18.0 mL
  • 9.6 mL
  • 24.0 mL

Correct answer: 18.0 mL

Explanation: The total loading dose required is 6 mg/kg * 60 kg = 360 mg. Since the available concentration is 25 mg/mL, the volume needed is 360 mg / 25 mg/mL = 14.4 mL.

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