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Canadian Pharmacist Qualifying Exam Practice · Question

A 35-year-old female, 5 weeks pregnant, presents with a severe migraine headache. She has no known allergies. She typically uses ibuprofen for migraines but is aware she cannot take it during pregnancy. What is the most appropriate acute migraine treatment for her at this stage of pregnancy?

Acetaminophen is generally considered the safest first-line option for acute migraine treatment during all trimesters of pregnancy. NSAIDs like ibuprofen and na

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Question: A 35-year-old female, 5 weeks pregnant, presents with a severe migraine headache. She has no known allergies. She typically uses ibuprofen for migraines but is aware she cannot take it during pregnancy. What is the most appropriate acute migraine treatment for her at this stage of pregnancy?

Answer options:

  • Aspirin
  • Sumatriptan ✅ Acetaminophen
  • Naproxen

Correct answer: Acetaminophen

Explanation: Acetaminophen is generally considered the safest first-line option for acute migraine treatment during all trimesters of pregnancy. NSAIDs like ibuprofen and naproxen should be avoided, especially in the third trimester, and triptans are generally reserved for when other options fail.

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