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Canadian Pharmacist Qualifying Exam Practice · Question

A 32-year-old breastfeeding mother, 3 months postpartum, presents with localized breast pain, redness, and fever (38.5°C), consistent with mastitis. She has no known drug allergies. What is the most appropriate antibiotic choice for this condition that is compatible with breastfeeding?

Amoxicillin-clavulanate is a first-line antibiotic for mastitis and is considered compatible with breastfeeding by most guidelines, with minimal risk to the inf

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Question: A 32-year-old breastfeeding mother, 3 months postpartum, presents with localized breast pain, redness, and fever (38.5°C), consistent with mastitis. She has no known drug allergies. What is the most appropriate antibiotic choice for this condition that is compatible with breastfeeding?

Answer options:

  • Metronidazole ✅ Amoxicillin-clavulanate
  • Ciprofloxacin
  • Doxycycline

Correct answer: Amoxicillin-clavulanate

Explanation: Amoxicillin-clavulanate is a first-line antibiotic for mastitis and is considered compatible with breastfeeding by most guidelines, with minimal risk to the infant. Ciprofloxacin and doxycycline are generally less preferred due to potential risks to the infant or decreased efficacy for common mastitis pathogens.

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