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Canadian Pharmacist Qualifying Exam Practice · Question

Which of the following drug classes is most associated with causing discolouration of teeth in children?

Tetracyclines are known to chelate with calcium ions, leading to permanent discolouration of developing teeth if given to children under 8 years of age.

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Question: Which of the following drug classes is most associated with causing discolouration of teeth in children?

Answer options: ✅ Tetracyclines

  • Penicillins
  • Macrolides
  • Cephalosporins

Correct answer: Tetracyclines

Explanation: Tetracyclines are known to chelate with calcium ions, leading to permanent discolouration of developing teeth if given to children under 8 years of age.

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