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Canadian Pharmacist Qualifying Exam Practice · Question

What common over-the-counter medication might worsen symptoms in a patient with benign prostatic hyperplasia (BPH)?

Alpha-adrenergic agonists like decongestants can constrict the smooth muscle in the prostate and bladder neck, worsening urinary outflow obstruction in BPH.

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Question: What common over-the-counter medication might worsen symptoms in a patient with benign prostatic hyperplasia (BPH)?

Answer options: ✅ Decongestants (e.g., pseudoephedrine)

  • Acetaminophen
  • Loperamide
  • Antacids

Correct answer: Decongestants (e.g., pseudoephedrine)

Explanation: Alpha-adrenergic agonists like decongestants can constrict the smooth muscle in the prostate and bladder neck, worsening urinary outflow obstruction in BPH.

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