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Canadian Pharmacist Qualifying Exam Practice · Question

What is the primary role of naloxone in opioid overdose management?

Naloxone is an opioid antagonist that rapidly reverses the effects of opioid overdose, primarily respiratory depression and central nervous system depression, b

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Question: What is the primary role of naloxone in opioid overdose management?

Answer options: ✅ To reverse respiratory and CNS depression by antagonizing opioid receptors.

  • To prevent opioid withdrawal symptoms in dependent individuals.
  • To potentiate the effects of other emergency medications.
  • To reduce pain perception during an overdose event.

Correct answer: To reverse respiratory and CNS depression by antagonizing opioid receptors.

Explanation: Naloxone is an opioid antagonist that rapidly reverses the effects of opioid overdose, primarily respiratory depression and central nervous system depression, by competing for opioid receptor binding sites.

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