Canadian Pharmacist Qualifying Exam Practice · Question
A patient with a penicillin allergy requires antibiotic treatment for a severe infection. Which of the following antibiotics is generally considered safe to use?
Azithromycin is a macrolide antibiotic and has no cross-reactivity with penicillins. Cephalexin and piperacillin are beta-lactams and carry a risk of cross-reac
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Question: A patient with a penicillin allergy requires antibiotic treatment for a severe infection. Which of the following antibiotics is generally considered safe to use?
Answer options:
- Amoxicillin
- Cephalexin ✅ Azithromycin
- Piperacillin/tazobactam
Correct answer: Azithromycin
Explanation: Azithromycin is a macrolide antibiotic and has no cross-reactivity with penicillins. Cephalexin and piperacillin are beta-lactams and carry a risk of cross-reactivity.
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