Canadian Pharmacist Qualifying Exam Practice · Question
A 58-year-old male presents to your community pharmacy. He is a heavy smoker (2 packs/day for 35 years) and is motivated to quit. He reports no known medical conditions, allergies, or current medications. He asks for your advice on the most effective single agent for smoking cessation. Which of the following would be the most appropriate recommendation?
Varenicline is generally considered the most effective single agent for smoking cessation based on meta-analyses and clinical trials. It works by acting as a pa
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Question: A 58-year-old male presents to your community pharmacy. He is a heavy smoker (2 packs/day for 35 years) and is motivated to quit. He reports no known medical conditions, allergies, or current medications. He asks for your advice on the most effective single agent for smoking cessation. Which of the following would be the most appropriate recommendation?
Answer options: ✅ Varenicline (Champix)
- Nicotine gum
- Bupropion (Zyban)
- Nicotine patch
Correct answer: Varenicline (Champix)
Explanation: Varenicline is generally considered the most effective single agent for smoking cessation based on meta-analyses and clinical trials. It works by acting as a partial agonist at nicotinic acetylcholine receptors, reducing withdrawal symptoms and the pleasure associated with smoking.
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