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Canadian Pharmacist Qualifying Exam Practice · Question

A patient with newly diagnosed type 2 diabetes is starting metformin. What is the most important counseling point regarding gastrointestinal side effects?

Metformin often causes gastrointestinal side effects; titrating the dose slowly and taking it with food can help mitigate these effects.

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Question: A patient with newly diagnosed type 2 diabetes is starting metformin. What is the most important counseling point regarding gastrointestinal side effects?

Answer options:

  • Take medication on an empty stomach
  • Increase dosage rapidly to achieve effect ✅ Titrate dosage slowly and take with food
  • Expect severe constipation

Correct answer: Titrate dosage slowly and take with food

Explanation: Metformin often causes gastrointestinal side effects; titrating the dose slowly and taking it with food can help mitigate these effects.

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