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Canadian Pharmacist Qualifying Exam Practice · Question

A patient with depression initiates therapy with an SSRI. How long should the patient be advised it typically takes to see a noticeable improvement in symptoms?

While some side effects may appear earlier, the therapeutic effects of SSRIs for depression typically take 4 to 6 weeks to become noticeable. This is important

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Question: A patient with depression initiates therapy with an SSRI. How long should the patient be advised it typically takes to see a noticeable improvement in symptoms?

Answer options:

  • Within 24-48 hours
  • 1 to 2 weeks ✅ 4 to 6 weeks
  • 3 to 6 months

Correct answer: 4 to 6 weeks

Explanation: While some side effects may appear earlier, the therapeutic effects of SSRIs for depression typically take 4 to 6 weeks to become noticeable. This is important for patient adherence.

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