Canadian Pharmacist Qualifying Exam Practice · Question
Tetracyclines should NOT be taken with:
Polyvalent cations (Ca, Mg, Al, Fe) chelate tetracyclines and quinolones, reducing absorption. Separate by 2 hours.
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Question: Tetracyclines should NOT be taken with:
Answer options:
- Water ✅ Dairy products, antacids, iron (form chelates)
- Bread
- Vegetables
Correct answer: Dairy products, antacids, iron (form chelates)
Explanation: Polyvalent cations (Ca, Mg, Al, Fe) chelate tetracyclines and quinolones, reducing absorption. Separate by 2 hours.
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